Leave-one-out cross validation test to determine the best fitted regression model.

<p>(A) Simulation curve for fixed 0.1 <i>C_R</i>+ additional <i>C_I</i> with all other parameters set to the default values and best fit regression curves for different degree of polynomials, (B) Root mean square error values for the leave-one-out cross validation (5 time points for each run, 10 independent runs for 25 µs), (C) Root mean square error values for the leave-one-out cross validation for simultaneous variation in <i>α</i> and C (five <i>α</i> values:1.6, 1.8, 2.0, 2.2, 2.4) and (eight <i>C</i> values: 0.1, 0.15, …, 0.45).