Serum cholesterol and testosterone levels in murine cohorts receiving cholesterol targeted treatment.

<p>(<b>A</b>) Mean cholesterol levels (with standard deviation and range) in mice randomized to 12 weeks of treatment with the indicated combinations of a low fat/no cholesterol diet (LFNC) or high fat/high cholesterol diet (HFHC) ± ezetimibe (drug). One way ANOVA with a post test for linear trend was used to compare values in the four treatment groups. P values<0.05 were considered significant. (<b>B</b>) Measurement of serum testosterone levels by ELISA in mice receiving the indicated HFHC or LFNC diet (n = 10/group). Data are presented as testosterone (T) levels (ng/ml) vs. diet group ± SE. Differences between mice fed the two diets were not statistically significant (unpaired two sample t-test).