<p>At each generation, CSCs can divide symmetrically, giving rise to two CSCs with probability or to two CCs with probability , or asymmetrically with probability giving rise to a CSC and a CC. Cancer cells can only divide a finite number of times (in the figure ), after that they become senescent. Senescent cells die with probability at each generation.</p
<p>(<b>A</b>) Schematic diagram shows the cell classification based on generation and CSC marker exp...
<p>Case 1 simulations, in which stem cell proliferation is increased ( = 0.07/day), are plotted with...
<div><p>The cancer stem cell (CSC) model depicts that tumors are hierarchically organized and mainta...
The Cancer Stem Cell (CSC) hypothesis has gained credibility within the cancer research community. A...
In this chapter, we will use multitype branching processes with mutation to model cancer. With cance...
Briefly, the cancer cell population is initiated by a single “wild type” (WT) cell, denoted as “0”. ...
<p>Schematic representation of the cell processes considered in the model of tumor growth (symmetric...
Cancer Stem Cells (CSC), a subset of cancer cells resembling normal stem cells with self-renewal and...
Cancer Stem Cells (CSC), a subset of cancer cells resembling normal stem cells with self-renewal and...
<div><p>Cells of different organs at different ages have an intrinsic set of kinetics that dictates ...
<div><p>Tumors are defined by their intense proliferation, but sometimes cancer cells turn senescent...
International audienceThe cancer stem cell hypothesis states that tumors are maintained by a small s...
<div><p>There is compelling biological data to suggest that cancer arises from a series of mutations...
International audienceThe clonal evolution (CE) model and the cancer stem cell (CSC) model are two i...
Abstract Cancer stem cells (CSCs) drive tumor progression, metastases, treatment resistance, and rec...
<p>(<b>A</b>) Schematic diagram shows the cell classification based on generation and CSC marker exp...
<p>Case 1 simulations, in which stem cell proliferation is increased ( = 0.07/day), are plotted with...
<div><p>The cancer stem cell (CSC) model depicts that tumors are hierarchically organized and mainta...
The Cancer Stem Cell (CSC) hypothesis has gained credibility within the cancer research community. A...
In this chapter, we will use multitype branching processes with mutation to model cancer. With cance...
Briefly, the cancer cell population is initiated by a single “wild type” (WT) cell, denoted as “0”. ...
<p>Schematic representation of the cell processes considered in the model of tumor growth (symmetric...
Cancer Stem Cells (CSC), a subset of cancer cells resembling normal stem cells with self-renewal and...
Cancer Stem Cells (CSC), a subset of cancer cells resembling normal stem cells with self-renewal and...
<div><p>Cells of different organs at different ages have an intrinsic set of kinetics that dictates ...
<div><p>Tumors are defined by their intense proliferation, but sometimes cancer cells turn senescent...
International audienceThe cancer stem cell hypothesis states that tumors are maintained by a small s...
<div><p>There is compelling biological data to suggest that cancer arises from a series of mutations...
International audienceThe clonal evolution (CE) model and the cancer stem cell (CSC) model are two i...
Abstract Cancer stem cells (CSCs) drive tumor progression, metastases, treatment resistance, and rec...
<p>(<b>A</b>) Schematic diagram shows the cell classification based on generation and CSC marker exp...
<p>Case 1 simulations, in which stem cell proliferation is increased ( = 0.07/day), are plotted with...
<div><p>The cancer stem cell (CSC) model depicts that tumors are hierarchically organized and mainta...