Metabolic conditions differentiate ΔΨm-loss in response to TG.

<p><i>A</i>, In the glucose condition STHdh^Q111 cells undergo ΔΨm-loss in response to TG at a significantly faster rate than STHdh^Q7 cells. In the pyruvate condition, ΔΨm of both cell types shows similar kinetics in response to TG. Arrows indicate the point at which ΔΨm begins to drop below the baseline. <i>n</i> = 4. <i>B</i>, RSG slightly but significantly delays TG-induced ΔΨm-loss in glucose and pyruvate conditions. GW9662 abrogates the delayed ΔΨm-loss by RSG treatment. <i>n</i> = 5–9. Data shown are mean ± SE. * <i>P</i><0.05.