<p>Differences shown in 5 kb-long intervals along the treponemal chromosome. Please note that the numbers of nucleotide changes (shown in bp) are for 7 intervals artificially terminated at 100 nt; the real values are shown next to corresponding vertical columns.</p
(a) Within-host nucleotide differences over 6-month timescales. The blue line shows the distribution...
<p>The variations that appear in greater proportion are missense, followed by those located in the i...
*<p>, Indicates synonymous mutations</p>†<p>, indicates nucleotide changes in non-coding region</p
<p>Each grey bar represents one single nucleotide difference between the two clones detected in the ...
<p>The figure shows the ratio between observed and expected number of mononucleotide repeats (<i>y</...
<p>N is number of sequences obtained for each gene in the overall study and in each of the seven col...
<p>In <b>A</b>, we plotted the observed levels of sequence diversity in 100 kb windows throughout th...
<p>The position of the differences in each genome is indicated along with the size of the change, in...
Is) were obtained with 5 kbp and 20 kbp sliding windows, overlapping every 2.5 kbp and 5 kbp, respec...
The expected numbers were calculated with a null-model that conserved the amino acid sequence and th...
<p>Nucleotide diversity in the (A) surface gene, (B) BCP/PC region and (C) X gene has been compared....
<p>Average number of nucleotide differences between ITS1 dataset sequences of closest related groups...
<p>The positions in the genome of BA71 and BA71V of the sequences affected are indicated along with ...
<p>Lower panel shows normalized frequencies of 256 tetranucleotides for each genome, upper panel sho...
<p>The thin dashed line shows an approximation by a single -exponential, while the thick dashed line...
(a) Within-host nucleotide differences over 6-month timescales. The blue line shows the distribution...
<p>The variations that appear in greater proportion are missense, followed by those located in the i...
*<p>, Indicates synonymous mutations</p>†<p>, indicates nucleotide changes in non-coding region</p
<p>Each grey bar represents one single nucleotide difference between the two clones detected in the ...
<p>The figure shows the ratio between observed and expected number of mononucleotide repeats (<i>y</...
<p>N is number of sequences obtained for each gene in the overall study and in each of the seven col...
<p>In <b>A</b>, we plotted the observed levels of sequence diversity in 100 kb windows throughout th...
<p>The position of the differences in each genome is indicated along with the size of the change, in...
Is) were obtained with 5 kbp and 20 kbp sliding windows, overlapping every 2.5 kbp and 5 kbp, respec...
The expected numbers were calculated with a null-model that conserved the amino acid sequence and th...
<p>Nucleotide diversity in the (A) surface gene, (B) BCP/PC region and (C) X gene has been compared....
<p>Average number of nucleotide differences between ITS1 dataset sequences of closest related groups...
<p>The positions in the genome of BA71 and BA71V of the sequences affected are indicated along with ...
<p>Lower panel shows normalized frequencies of 256 tetranucleotides for each genome, upper panel sho...
<p>The thin dashed line shows an approximation by a single -exponential, while the thick dashed line...
(a) Within-host nucleotide differences over 6-month timescales. The blue line shows the distribution...
<p>The variations that appear in greater proportion are missense, followed by those located in the i...
*<p>, Indicates synonymous mutations</p>†<p>, indicates nucleotide changes in non-coding region</p