Zoom views of the association results in the loci associated with IL-6 and ESR.
- Silvia Naitza (186150)
- Eleonora Porcu (186153)
- Maristella Steri (186157)
- Dennis D. Taub (186158)
- Antonella Mulas (145739)
- Xiang Xiao (44417)
- James Strait (186161)
- Mariano Dei (186165)
- Sandra Lai (186168)
- Fabio Busonero (186172)
- Andrea Maschio (186176)
- Gianluca Usala (186178)
- Magdalena Zoledziewska (166739)
- Carlo Sidore (145691)
- Ilenia Zara (166732)
- Maristella Pitzalis (166734)
- Alessia Loi (186187)
- Francesca Virdis (186191)
- Roberta Piras (186195)
- Francesca Deidda (186200)
- Michael B. Whalen (186204)
- Laura Crisponi (186209)
- Antonio Concas (186213)
- Carlo Podda (186216)
- Sergio Uzzau (186221)
- Paul Scheet (186223)
- Dan L. Longo (186226)
- Edward Lakatta (186230)
- Gonçalo R. Abecasis (36598)
- Antonio Cao (186234)
- David Schlessinger (2399)
- Manuela Uda (186237)
- Serena Sanna (145737)
- Francesco Cucca (145742)
DOIAbstract
<p>Each panel shows the association curve around the strongest SNP, which is highlighted with a purple dot. The SNPs are coloured according to their linkage disequilibrium (r<sup>2</sup>) with the top variant in the 1000 Genomes European data set, with symbols that reflect genomic annotation as indicated in the legend. Arrows highlight independent signals, if any, described in the manuscript; while light blue lines indicate the recombination rate, according to the right-hand Y axis. Genomic positions are as in build 37. Gene transcripts are annotated in the lower box. Plots were drawn using the standalone LocusZoom version <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002480#pgen.1002480-Pruim1" target="_blank"...
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