Intraperitoneal injection of BP180/CXVII-specific IgG induces blister formation in adult mice.

<p>Skin lesions, including blisters, erosions, and crusts developed on the (<b>A</b>) ear, (<b>B</b>) front leg and (<b>C</b>) periocular area in a BALB/c mouse pre-sensitized with rabbit IgG and subsequently receiving, over a period of 10 days, 6 i.p. injections of IgG, each containing 15 mg of IgG, from a rabbit immunized against murine BP180/CXVII. (<b>D, E, F</b>) A control mouse pre-sensitized with rabbit IgG and challenged with the same dose of normal rabbit IgG showed no skin alterations.