<p>The approach is as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030870#pone-0030870-g004" target="_blank">Figure 4</a> with differences due to the pattern created by the relationship between cyclin B1 and PHH3. A:interphase segmentation. B: mitotic segmentation.</p
<p>Data were first gated on single cells cells from 2C to 4C in DNA content (not shown) AND (Boolean...
<p>DNA histograms from K562 cells stained for single cyclins A2 (B) or B1 (C) or stained for both cy...
The timing mechanism for mitotic progression is still poorly understood. The spindle assembly checkp...
<p>To segment mitotic cells stained for cyclins A2, B1, and PHH3, it is necessary to view the data i...
<p>Samples from the same Molt4 population as shown in previous figures were stained for cyclins A2, ...
<p>Molt4 cells were stained as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.p...
<p>Overlays of expression profiles for PHH3 (A, B) from the data set Molt4 cells stained for cyclin ...
<p>(A) Initial mitotic-like arrangement, constituted by 6 copies of model human chromosome 19. Follo...
<p>All panels show Cyclin B protein in green as a marker for cells between S-phase and mitotic metap...
<p>(A) Time courses of levels of cyclin B1, Cdk1 activity, and Cdk1 Y15 phosphorylation. The cyclin ...
<p><b>A</b>. Representative images of mitotic BS-C-1 cells expressing GFP fusions of WT<sup>1–433</s...
<p><b>A, B, D, E, F</b>: total simulated levels (bound and free, inactive and active) of cyclins A a...
The mitotic biosensor (MBS) has an affinity for con-densed chromosomes, allowing us to assess the ti...
AbstractBackground: Degradation of the mitotic cyclins is a hallmark of the exit from mitosis. Induc...
SummaryThe timing mechanism for mitotic progression is still poorly understood. The spindle assembly...
<p>Data were first gated on single cells cells from 2C to 4C in DNA content (not shown) AND (Boolean...
<p>DNA histograms from K562 cells stained for single cyclins A2 (B) or B1 (C) or stained for both cy...
The timing mechanism for mitotic progression is still poorly understood. The spindle assembly checkp...
<p>To segment mitotic cells stained for cyclins A2, B1, and PHH3, it is necessary to view the data i...
<p>Samples from the same Molt4 population as shown in previous figures were stained for cyclins A2, ...
<p>Molt4 cells were stained as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.p...
<p>Overlays of expression profiles for PHH3 (A, B) from the data set Molt4 cells stained for cyclin ...
<p>(A) Initial mitotic-like arrangement, constituted by 6 copies of model human chromosome 19. Follo...
<p>All panels show Cyclin B protein in green as a marker for cells between S-phase and mitotic metap...
<p>(A) Time courses of levels of cyclin B1, Cdk1 activity, and Cdk1 Y15 phosphorylation. The cyclin ...
<p><b>A</b>. Representative images of mitotic BS-C-1 cells expressing GFP fusions of WT<sup>1–433</s...
<p><b>A, B, D, E, F</b>: total simulated levels (bound and free, inactive and active) of cyclins A a...
The mitotic biosensor (MBS) has an affinity for con-densed chromosomes, allowing us to assess the ti...
AbstractBackground: Degradation of the mitotic cyclins is a hallmark of the exit from mitosis. Induc...
SummaryThe timing mechanism for mitotic progression is still poorly understood. The spindle assembly...
<p>Data were first gated on single cells cells from 2C to 4C in DNA content (not shown) AND (Boolean...
<p>DNA histograms from K562 cells stained for single cyclins A2 (B) or B1 (C) or stained for both cy...
The timing mechanism for mitotic progression is still poorly understood. The spindle assembly checkp...