Differentially expressed miRNAs in irradiated PBL incubated in 1 g condition.

<p>(A) Number of radio-responsive miRNAs at 4 and 24 h after irradiation with 0.2 and 2Gy of γ-rays. (B) Percentage of dose-responsive miRNAs at the same time points. The expression level of each radio-responsive miRNA is the mean of expression values from six different donors/dose determined by the log2 (irradiated/non-irradiated) PBL. (C) Dendrogram showing radio-responsive miRNAs common to 0.2 and 2Gy of γ-rays, whose expression changed between 4 and 24 h after irradiation. Six different donors were analyzed for each dose, as indicated by the capital letters. The range of expression value is from -3.0 (green, down-regulation) to 3.0 (red, up-regulation). Grey boxes correspond to not available (N/A) fluorescent signal from the microarray platform.