a<p>Defined as total number of beam brakes for 16 flies in the DAM2 system over 24 h. Flies were reared at 29°C and assayed at the same temperature.</p>b<p>Protein deposition load determined by visual inspection with a fluorescence microscope of immunofluorescence of antibody detection, of histological sections of <i>Drosophila</i> heads at day 10 for <i>C155-Gal4/UAS-Aβ<sub>1–40</sub></i>, <i>C155-Gal4/UAS-Aβ<sub>1–42</sub></i>, <i>C155-Gal4/UAS-Aβ<sub>1–42</sub>;UAS-Aβ<sub>1–42</sub></i>, <i>C155-Gal4/UAS-tau</i>; and day 5 for <i>C155-Gal4/UAS-Aβ<sub>1–42 E22G</sub></i>. At least 20 fly heads were assayed for each genotype. +++, extensive; ++, intermediate; + detectable; −, not detected; n.a., not assayed.</p>c<p>Aggregate deposition loa...
Alzheimer’s is a devastating disease with few treatments.1 Some studies support the therapeutic effe...
This study was aimed at evaluating different modulators of amyloid-beta aggregation in Drosophila me...
Transgenic models of Alzheimer’s disease (AD) have made significant contributions to our understandi...
<p>Micrographs of <i>Drosophila</i> brains taken with 100× objective showing fluorescence from cell ...
<p>Amyloid fibrillation index as individual spectral shift (A, C, and E) and mean spectral shift wit...
<p>Quantification of Aβ-peptide in aged flies was performed using the Meso Scale Discovery (MSD) imm...
<div><p>The pathology of Alzheimer's disease (AD) is characterized by the presence of extracellular ...
The pathology of Alzheimer's disease (AD) is characterized by the presence of extracellular deposits...
The pathology of Alzheimer's disease (AD) is characterized by the presence of extracellular deposits...
The pathology of Alzheimers disease (AD) is characterized by the presence of extracellular deposits ...
<p>Survival trajectories of transgenic <i>C155-Gal4 Drosophila</i> for different curcumin treatments...
In this thesis Drosophila melanogaster (the fruit fly) has been used as a model organism to study th...
Transgenic models of Alzheimer's disease (AD) have made significant contributions to our understandi...
The term neurodegeneration refers to the progressive loss of neurons leading to the onset of irrever...
Amyloid diseases are caused by protein misfolding and aggregation. To date there are 27 known protei...
Alzheimer’s is a devastating disease with few treatments.1 Some studies support the therapeutic effe...
This study was aimed at evaluating different modulators of amyloid-beta aggregation in Drosophila me...
Transgenic models of Alzheimer’s disease (AD) have made significant contributions to our understandi...
<p>Micrographs of <i>Drosophila</i> brains taken with 100× objective showing fluorescence from cell ...
<p>Amyloid fibrillation index as individual spectral shift (A, C, and E) and mean spectral shift wit...
<p>Quantification of Aβ-peptide in aged flies was performed using the Meso Scale Discovery (MSD) imm...
<div><p>The pathology of Alzheimer's disease (AD) is characterized by the presence of extracellular ...
The pathology of Alzheimer's disease (AD) is characterized by the presence of extracellular deposits...
The pathology of Alzheimer's disease (AD) is characterized by the presence of extracellular deposits...
The pathology of Alzheimers disease (AD) is characterized by the presence of extracellular deposits ...
<p>Survival trajectories of transgenic <i>C155-Gal4 Drosophila</i> for different curcumin treatments...
In this thesis Drosophila melanogaster (the fruit fly) has been used as a model organism to study th...
Transgenic models of Alzheimer's disease (AD) have made significant contributions to our understandi...
The term neurodegeneration refers to the progressive loss of neurons leading to the onset of irrever...
Amyloid diseases are caused by protein misfolding and aggregation. To date there are 27 known protei...
Alzheimer’s is a devastating disease with few treatments.1 Some studies support the therapeutic effe...
This study was aimed at evaluating different modulators of amyloid-beta aggregation in Drosophila me...
Transgenic models of Alzheimer’s disease (AD) have made significant contributions to our understandi...