Computer simulations of arm function showing dependence on model parameters.

<p>A. Simulations of the effect on use after hypothetical changes in the confidence parameter as a result of therapy. Initial parameters values: = 0.6, = 3, = 3. For simplicity, we assumed here that therapy has only an effect on the parameter and not on use and performance (which it did in actual participants of the EXCITE trial <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002343#pcbi.1002343-Wolf1" target="_blank">[3]</a>). The increase in parameter from before to after therapy parallels the increase in this parameter in the delayed group of the EXCITE trial (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002343#pcbi-1002343-g004" target="_blank">Figure 4</a>). B. Parameter sensitivity analysis showing the asymptotic value of arm function <i>F</i> as a function of parameter for a number of values of . LP: limit point. The line labeled = 3 is generated by the same model as in A. For values of >3 the system behavior exhibits a non-stable range between the two limit points. For = 3.5 and = 5 for instance, arm function F converges to either a low or a high value.