Adoptively transferred RNEU_420–429-specific high avidity T cells enhance tumor clearance in FVB/N mice.

<p>The minimal tumorigenic dose was given to FVB/N mice on day 0; Cy was given on day 2; vaccine or mock vaccine was injected on day 3; high avidity or low avidity T cells were adoptively transferred on day 4. Treatment groups are indicated in the figures. (<b>A</b>) Tumor growth after high avidity T cell adoptive transfer into FVB/N mice. (<b>B</b>) Tumor growth after low avidity T cell adoptive transfer into FVB/N mice. Data was graphed as the tumor area vs. days (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031962#pone-0031962-g001" target="_blank">figures 1 A–B</a>) after adoptive transfer. * = p<0.05; ** = p<0.001. Experiments were repeated three times (n = 10 mice per group).