<p>Quantitation of (a) LRH-1, (b) GREB1 and (c) ERα mRNA expression in estrogen-deprived MCF-7 cells (control) or LRH-1 over-expressing (+LRH-1) MCF-7 cells treated with vehicle (veh) or 10 nM 17β-estradiol (E2) for 16 h. Data is presented as mean+SE, n = 3 separate experiments, triplicate treatments per experiment, **P<0.01, ***P<0.001 compared to vehicle control.</p
<p>ERα-expressing Hs578T and MCF-7 cells were treated with 10<sup>−10</sup> M estradiol and/or 40 ng...
<p>(a) EMSA showing binding of LRH-1 to the EREs present in the GREB1 promoter. Radiolabeled ERE1-GR...
<p>ChIP assays were performed in MCF7 cells transiently transfected with a consensus ERE and treated...
<p>MDA-MB-231 cells were transfected with empty vector (C) or expression vectors for LRH-1 alone (L)...
<p>Transcriptional activation of (a) 2×ERE and (b) GREB-ERE2 luciferase reporters by ERα and LRH-1 w...
<p>Cell proliferation was measured in pcDNA alone transfected, estrogen-deprived MCF-7 cells (contro...
<p>A, Western blotting detects a single band of ∼216 kD in E2-deprived MCF-7 cells treated with estr...
<p>MCF7 (ER+/PR+) and MDA-MB-231 (ER−/PR-) breast cancer cells were treated with 17β-estradiol (E2),...
<div><h3>Background</h3><p>Liver Receptor Homolog 1 (LRH-1, NR5A2) is an orphan nuclear receptor tha...
<p>A) Baseline mRNA expression of NFAT (c1–c4) in 1HAE<sub>0</sub> cells quantified by real-time PCR...
<p><b>Copyright information:</b></p><p>Taken from "Prenylation inhibitors stimulate both estrogen re...
<p>(A) Scheme of pre- and co-incubation treatment. (B) Pre-treatment of cells with AG18051 for 24 ho...
<p>E2 treatment increases GREB1 mRNA levels by approximately 43-fold after 48 h treatment (<a href="...
<p> Effect of the pure ER antagonist fulvestrant on the estrogen stimulated Y<sub>1</sub>R expressio...
Background. Estrogen plays a central role in breast cancer pathogenesis and many potent risk factors...
<p>ERα-expressing Hs578T and MCF-7 cells were treated with 10<sup>−10</sup> M estradiol and/or 40 ng...
<p>(a) EMSA showing binding of LRH-1 to the EREs present in the GREB1 promoter. Radiolabeled ERE1-GR...
<p>ChIP assays were performed in MCF7 cells transiently transfected with a consensus ERE and treated...
<p>MDA-MB-231 cells were transfected with empty vector (C) or expression vectors for LRH-1 alone (L)...
<p>Transcriptional activation of (a) 2×ERE and (b) GREB-ERE2 luciferase reporters by ERα and LRH-1 w...
<p>Cell proliferation was measured in pcDNA alone transfected, estrogen-deprived MCF-7 cells (contro...
<p>A, Western blotting detects a single band of ∼216 kD in E2-deprived MCF-7 cells treated with estr...
<p>MCF7 (ER+/PR+) and MDA-MB-231 (ER−/PR-) breast cancer cells were treated with 17β-estradiol (E2),...
<div><h3>Background</h3><p>Liver Receptor Homolog 1 (LRH-1, NR5A2) is an orphan nuclear receptor tha...
<p>A) Baseline mRNA expression of NFAT (c1–c4) in 1HAE<sub>0</sub> cells quantified by real-time PCR...
<p><b>Copyright information:</b></p><p>Taken from "Prenylation inhibitors stimulate both estrogen re...
<p>(A) Scheme of pre- and co-incubation treatment. (B) Pre-treatment of cells with AG18051 for 24 ho...
<p>E2 treatment increases GREB1 mRNA levels by approximately 43-fold after 48 h treatment (<a href="...
<p> Effect of the pure ER antagonist fulvestrant on the estrogen stimulated Y<sub>1</sub>R expressio...
Background. Estrogen plays a central role in breast cancer pathogenesis and many potent risk factors...
<p>ERα-expressing Hs578T and MCF-7 cells were treated with 10<sup>−10</sup> M estradiol and/or 40 ng...
<p>(a) EMSA showing binding of LRH-1 to the EREs present in the GREB1 promoter. Radiolabeled ERE1-GR...
<p>ChIP assays were performed in MCF7 cells transiently transfected with a consensus ERE and treated...