<p>Results for 100 simulations of 250 family trios as a function of the recombination rate using the dominant and one-locus genetic model and haplotypes of lengths (left plot), (plot in the middle) and (right plot). A nominal level of and a relative risk of were used for all plots. Results for and are plotted in purple circles and blue triangles respectively. Dashed lines show results for the data subset (125 trios randomly chosen) used to build the model while solid lines show results for a second data subset (the remaining 125 trios) used to test reproducibility.</p
<p>The accuracy of the recombination rate estimate for model RS3, containing infrequent but strong s...
<div><p>Multimarker Transmission/Disequilibrium Tests (TDTs) are very robust association tests to po...
<p><b>Copyright information:</b></p><p>Taken from "A hierarchical and modular approach to the discov...
<p>Panel A shows the linkage disequilibrium block analysis for the 12 SNPs with <i>P<sub>GWAS</sub><...
(A) Distribution of chromosome Spearman’s rank correlations between the number of genes and the reco...
<p>Results for rare variants are shown in red; for the top hit among common variants, results are sh...
The probability model of parental transmission (of a multiallelic marker) to affected offspring has ...
<p>SNPs plotted with their –log<sub>10</sub> (<i>P</i>-values) in the GWAS based on their physical c...
We have performed simulations to assess the performance of three population genetics approximate-lik...
Background: Spurious associations between single nucleotide polymorphisms and phenotypes are a major...
The arrival of publicly available genome-wide variation data is creating new opportunities for recon...
As population structure can result in spurious associations, it has constrained the use of associati...
<p>Subpanels (A) and (B) contain contour plots showing the proportion of heritability explained () b...
<p>Odds ratios were simulated for 50,000 times for each pair of a genotype concordance (from 0.94 to...
Complex disorders are typically characterized by multiple phenotypes. Analyzing these phenotypes joi...
<p>The accuracy of the recombination rate estimate for model RS3, containing infrequent but strong s...
<div><p>Multimarker Transmission/Disequilibrium Tests (TDTs) are very robust association tests to po...
<p><b>Copyright information:</b></p><p>Taken from "A hierarchical and modular approach to the discov...
<p>Panel A shows the linkage disequilibrium block analysis for the 12 SNPs with <i>P<sub>GWAS</sub><...
(A) Distribution of chromosome Spearman’s rank correlations between the number of genes and the reco...
<p>Results for rare variants are shown in red; for the top hit among common variants, results are sh...
The probability model of parental transmission (of a multiallelic marker) to affected offspring has ...
<p>SNPs plotted with their –log<sub>10</sub> (<i>P</i>-values) in the GWAS based on their physical c...
We have performed simulations to assess the performance of three population genetics approximate-lik...
Background: Spurious associations between single nucleotide polymorphisms and phenotypes are a major...
The arrival of publicly available genome-wide variation data is creating new opportunities for recon...
As population structure can result in spurious associations, it has constrained the use of associati...
<p>Subpanels (A) and (B) contain contour plots showing the proportion of heritability explained () b...
<p>Odds ratios were simulated for 50,000 times for each pair of a genotype concordance (from 0.94 to...
Complex disorders are typically characterized by multiple phenotypes. Analyzing these phenotypes joi...
<p>The accuracy of the recombination rate estimate for model RS3, containing infrequent but strong s...
<div><p>Multimarker Transmission/Disequilibrium Tests (TDTs) are very robust association tests to po...
<p><b>Copyright information:</b></p><p>Taken from "A hierarchical and modular approach to the discov...