b<p>Moderate and high AKT1 expression as defined in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030427#pone-0030427-t003" target="_blank">Table 3</a>.</p>c<p>Moderate and high AKT2 expression as defined in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030427#pone-0030427-t003" target="_blank">Table 3</a>.</p>d<p>Moderate and high PIK3CA expression as defined in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030427#pone-0030427-t003" target="_blank">Table 3</a>.</p>e<p>PTEN loss as defined in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030427#pone-0030427-t003" target="_blank">Table 3</a>.</p
AbstractRecruiting Akt to the membrane-bound phosphatidylinositol (3,4,5) trisphosphate (PIP3) is re...
PTEN is inactivated in a subset of lung cancer; therefore, we investigated the involvement of PTEN i...
<p>Computational simulation of Akt phosphorylation (pAkt) in NSCLC that involve loss of PTEN (at 50 ...
a<p>High AKT1 expression as defined in the manuscript.</p>b<p>High AKT2 expression as defined in the...
a<p>AKT activation was evaluated with as pS473 positivity and scored as negative (<10% of positive t...
<p>Representative western blot bands (<b>A</b>) are shown of p-Akt and β-actin as well as densitomet...
<p>U87MG cells expressing WT-PTEN, C124S-PTEN or G129E-PTEN and mock-treated were incubated in high ...
<p>(A) Distribution of alterations in <i>PIK3CA</i>, <i>AKT1</i> and PTEN across 75 matched primary ...
<p>(a) The immunoblot of proteins from cell lysates of the HeLa cells transfected with serial diluti...
AbstractRecruiting Akt to the membrane-bound phosphatidylinositol (3,4,5) trisphosphate (PIP3) is re...
To identify novel effectors and processes regulated by PI3K pathway activation, we performed an unbi...
目的:探讨磷酸化Akt(p-Akt)与PTEN表达在非小细胞肺癌(NSCLC)侵袭、转移中的作用及其相关关系.方法:应用免疫组织化学SP法检测20例正常肺组织和102例非小细胞肺癌癌组织中p-Akt和...
<p>An antibody against total Akt was used as control. The potent PI3-K-inhibitor Ly294002 (50 nM) wa...
<p>We observed a two-fold reduction in PTEN mRNA expression at 24 h and 28 h compared to baseline (0...
<p>Correlation among <i>PIK3CA</i> mutation, amplification and expression of PI3K p110α, p-Akt,m TOR...
AbstractRecruiting Akt to the membrane-bound phosphatidylinositol (3,4,5) trisphosphate (PIP3) is re...
PTEN is inactivated in a subset of lung cancer; therefore, we investigated the involvement of PTEN i...
<p>Computational simulation of Akt phosphorylation (pAkt) in NSCLC that involve loss of PTEN (at 50 ...
a<p>High AKT1 expression as defined in the manuscript.</p>b<p>High AKT2 expression as defined in the...
a<p>AKT activation was evaluated with as pS473 positivity and scored as negative (<10% of positive t...
<p>Representative western blot bands (<b>A</b>) are shown of p-Akt and β-actin as well as densitomet...
<p>U87MG cells expressing WT-PTEN, C124S-PTEN or G129E-PTEN and mock-treated were incubated in high ...
<p>(A) Distribution of alterations in <i>PIK3CA</i>, <i>AKT1</i> and PTEN across 75 matched primary ...
<p>(a) The immunoblot of proteins from cell lysates of the HeLa cells transfected with serial diluti...
AbstractRecruiting Akt to the membrane-bound phosphatidylinositol (3,4,5) trisphosphate (PIP3) is re...
To identify novel effectors and processes regulated by PI3K pathway activation, we performed an unbi...
目的:探讨磷酸化Akt(p-Akt)与PTEN表达在非小细胞肺癌(NSCLC)侵袭、转移中的作用及其相关关系.方法:应用免疫组织化学SP法检测20例正常肺组织和102例非小细胞肺癌癌组织中p-Akt和...
<p>An antibody against total Akt was used as control. The potent PI3-K-inhibitor Ly294002 (50 nM) wa...
<p>We observed a two-fold reduction in PTEN mRNA expression at 24 h and 28 h compared to baseline (0...
<p>Correlation among <i>PIK3CA</i> mutation, amplification and expression of PI3K p110α, p-Akt,m TOR...
AbstractRecruiting Akt to the membrane-bound phosphatidylinositol (3,4,5) trisphosphate (PIP3) is re...
PTEN is inactivated in a subset of lung cancer; therefore, we investigated the involvement of PTEN i...
<p>Computational simulation of Akt phosphorylation (pAkt) in NSCLC that involve loss of PTEN (at 50 ...