<p>Shown are representative retinal sections of single ommatidia from wild-type and <i>shibire<sup>ts1</sup></i> mutants. Dark-raised flies were first incubated at 30°C to block endocytosis in <i>shi<sup>ts1</sup></i>, indicated by paralysis. Flies continued to be incubated at 30°C but either remained in the dark or were light-exposed for 2 hours. Tissue sections were immunostained for TRPL. TRPL displayed normal light-induced translocation from the rhabdomere to the neighboring stalk membrane. Multiple tissue sections were taken from 14 eyes from nine flies (wild-type, Dark), 10 eyes from 8 flies (wild-type, Light), 10 eyes from 7 flies (<i>shibire<sup>ts1</sup></i>, Dark), 15 eyes from 10 flies (<i>shibire<sup>ts1</sup></i>, Light).</p
<p>(A-E) ERG paradigm that elicits “on” and “off” transients (arrows) in (A) wt (<i>w</i><sup><i>111...
, TRP and TRPL are the light-activated channels in photoreceptors. While TRP is statically localized...
<p>(A) Whole mount staining of photoreceptors of flies raised in the dark. Note that Rh1, InaD, and ...
<p>(A) Water immersion microscopy images of the Rh1-eGFP and TRP-eGFP fluorescence in the eyes of wi...
<div><h3>Background</h3><p>TRP channels function as key mediators of sensory transduction and other ...
<div><h3>Background</h3><p>TRP channels function as key mediators of sensory transduction and other ...
TRP channels function as key mediators of sensory transduction and other cellular signaling pathways...
<p>(A) Water immersion microscopy images of TRPL-eGFP fluorescence in white colored (<i>white</i><su...
<p>(A) <i>hs-inaD</i> transgenic flies (in an <i>inaD<sup>1</sup></i> null background) express INAD ...
<p>(A) Western blots of proteins regulating phototransduction. Protein was extracted from heads of f...
<p>(A) In adult flies, blue light triggers the conformational change of Rh to metaRh, whereas orange...
<p>(A) Rh1 is aberrantly distributed in <i>Vps26<sup>1</sup></i> mutants. Dark-reared control (iso) ...
<p>Newly eclosed flies were exposed to bright light (2900 lux) for 90 min. A single ommatidium prepa...
, TRP and TRPL are the light-activated channels in photoreceptors. While TRP is statically localized...
The Drosophila and Lucilia photoreceptor mutants, trp and nss, respond like wild-type flies to a sho...
<p>(A-E) ERG paradigm that elicits “on” and “off” transients (arrows) in (A) wt (<i>w</i><sup><i>111...
, TRP and TRPL are the light-activated channels in photoreceptors. While TRP is statically localized...
<p>(A) Whole mount staining of photoreceptors of flies raised in the dark. Note that Rh1, InaD, and ...
<p>(A) Water immersion microscopy images of the Rh1-eGFP and TRP-eGFP fluorescence in the eyes of wi...
<div><h3>Background</h3><p>TRP channels function as key mediators of sensory transduction and other ...
<div><h3>Background</h3><p>TRP channels function as key mediators of sensory transduction and other ...
TRP channels function as key mediators of sensory transduction and other cellular signaling pathways...
<p>(A) Water immersion microscopy images of TRPL-eGFP fluorescence in white colored (<i>white</i><su...
<p>(A) <i>hs-inaD</i> transgenic flies (in an <i>inaD<sup>1</sup></i> null background) express INAD ...
<p>(A) Western blots of proteins regulating phototransduction. Protein was extracted from heads of f...
<p>(A) In adult flies, blue light triggers the conformational change of Rh to metaRh, whereas orange...
<p>(A) Rh1 is aberrantly distributed in <i>Vps26<sup>1</sup></i> mutants. Dark-reared control (iso) ...
<p>Newly eclosed flies were exposed to bright light (2900 lux) for 90 min. A single ommatidium prepa...
, TRP and TRPL are the light-activated channels in photoreceptors. While TRP is statically localized...
The Drosophila and Lucilia photoreceptor mutants, trp and nss, respond like wild-type flies to a sho...
<p>(A-E) ERG paradigm that elicits “on” and “off” transients (arrows) in (A) wt (<i>w</i><sup><i>111...
, TRP and TRPL are the light-activated channels in photoreceptors. While TRP is statically localized...
<p>(A) Whole mount staining of photoreceptors of flies raised in the dark. Note that Rh1, InaD, and ...