OK432 induced IL-12p70 production is TRIF dependent.
- Arnt-Ove Hovden (181836)
- Marie Karlsen (181843)
- Roland Jonsson (46896)
- Silke Appel (181849)
Publication date
February 2012
DOIAbstract
<p>Pre-treating the DC for 30 minutes at 37°C with an inhibitory peptide of TRIF signaling reduced the level of OK432 induced IL-12p70 production in a dose dependent manner compared to a control peptide and OK432. Concentrations higher than 20 µM had a toxic effect on the DC. Data from one representative donor is shown.</p
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