<p>(A) <i>miR-21</i>, (B) <i>miR-126</i> and (C) <i>miR-16</i> were measured using RT-qPCR in order to compare PDAC to normal pancreas for the miRNAs of interest. <i>MiR-21</i> is overexpressed in PDAC compared to normal pancreas tissue (*** <i>P</i><0.001). <i>MiR-126</i> and <i>miR-16</i> expression levels were not significantly different between PDAC and normal pancreas tissue. Samples included: normal pancreas (n = 9) and PDAC (n = 15). Box and Whiskers indicate median, minimum and maximum.</p
Pancreatic ductal adenocarcinoma (PDAC) is considered one of the most aggressive malignancies and ha...
<p>MiR-497 levels in pancreatic tissues were detected using ISH (200×). (<b>A</b>) Negative control....
<p>The expression levels of the 2 miRNAs (miR-21, and miR-133b) were measured by means of qRT-PCR in...
<p>This suggests that <i>miR-21</i> overexpression may be an early event in the formation of pancrea...
<p>(A) Average expression level of miR-26a in human PDAC specimens (<i>n</i> = 15) and normal pancre...
<p>(A, B) Mature miR-193b expression levels were measured by real-time PCR in PDAC samples (n = 11) ...
<p>MicroRNA levels were evaluated in triplicate by qRT-PCR to confirm expression changes identified ...
<p><b><i>Note</i>:</b> **<i>P</i> <0.01 PDAC tissue <i>vs</i>. normal pancreas tissues (Fisher’s exa...
<p>(A) Validation of miRNAs by qRT-PCR: Box plots representing the tissue expression level of four m...
Ductal adenocarcinoma (PDAC) is the most common primary pancreatic neoplasm. It's frequently diagnos...
<p>(A) Average expression level of miR-371-5p in human PDAC specimens (<i>n</i> = 15) and normal pan...
<p>The Y-axis (log<sub>10</sub> scale) represents the relative expression of each miRNA normalized t...
Small nucleolar RNA U91 is a new internal control for accurate microRNAs quantification in pancreati...
cules that are involved in the regulation of many cellu-lar processes, including those related to hu...
<p>(A) MiRNA microarray expression analyses were performed using Illumina microarray to evaluate the...
Pancreatic ductal adenocarcinoma (PDAC) is considered one of the most aggressive malignancies and ha...
<p>MiR-497 levels in pancreatic tissues were detected using ISH (200×). (<b>A</b>) Negative control....
<p>The expression levels of the 2 miRNAs (miR-21, and miR-133b) were measured by means of qRT-PCR in...
<p>This suggests that <i>miR-21</i> overexpression may be an early event in the formation of pancrea...
<p>(A) Average expression level of miR-26a in human PDAC specimens (<i>n</i> = 15) and normal pancre...
<p>(A, B) Mature miR-193b expression levels were measured by real-time PCR in PDAC samples (n = 11) ...
<p>MicroRNA levels were evaluated in triplicate by qRT-PCR to confirm expression changes identified ...
<p><b><i>Note</i>:</b> **<i>P</i> <0.01 PDAC tissue <i>vs</i>. normal pancreas tissues (Fisher’s exa...
<p>(A) Validation of miRNAs by qRT-PCR: Box plots representing the tissue expression level of four m...
Ductal adenocarcinoma (PDAC) is the most common primary pancreatic neoplasm. It's frequently diagnos...
<p>(A) Average expression level of miR-371-5p in human PDAC specimens (<i>n</i> = 15) and normal pan...
<p>The Y-axis (log<sub>10</sub> scale) represents the relative expression of each miRNA normalized t...
Small nucleolar RNA U91 is a new internal control for accurate microRNAs quantification in pancreati...
cules that are involved in the regulation of many cellu-lar processes, including those related to hu...
<p>(A) MiRNA microarray expression analyses were performed using Illumina microarray to evaluate the...
Pancreatic ductal adenocarcinoma (PDAC) is considered one of the most aggressive malignancies and ha...
<p>MiR-497 levels in pancreatic tissues were detected using ISH (200×). (<b>A</b>) Negative control....
<p>The expression levels of the 2 miRNAs (miR-21, and miR-133b) were measured by means of qRT-PCR in...