Tiled fluorescent micrographs of coronal cryosections obtained from the left lungs of mice.

<p>Mice received either an IV (A, C, E, G) or IT (B, D, F, H) dose of a mixture of Hoe and MTR. <b>A</b>) DAPI channel fluorescence image showing Hoe distribution following IV administration; <b>B</b>) DAPI channel fluorescence image showing Hoe distribution following IT administration; <b>C</b>) High magnification view of the boxed region in A; <b>D</b>) High magnification view of the boxed region in B; <b>E</b>) TRITC channel fluorescence image showing MTR distribution following IV administration; <b>F</b>) TRITC channel fluorescence image showing MTR distribution following IT administration; <b>G</b>) High magnification view of the boxed region in E; <b>H</b>) High magnification view of the boxed region in F. Scale bar = 1 mm. Asterisks mark the cross-sections of the airways, apparent as ellipsoids at high magnification.