ROS Pathway Analysis of lal−/− bone marrow MDSCs.

<p><b>A</b>). Differential gene expression of CD11b⁺Ly6G⁺ MDSCs from the bone marrow of <i>lal+/+</i> mice and <i>lal−/−</i> mice was analyzed by Ingenuity Pathway Analysis. Changed genes in the nitric oxide and reactive oxygen species production genes are presented; <b>B</b>). ROS production in CD11b⁺Ly6G⁺ MDSCs from the bone marrow of <i>lal+/+</i> mice and <i>lal−/−</i> mice. The ROS signal was statistically analyzed by mean fluorescent intensity (MFI). Results are means of 4 independent FACS experiments. n = 4, **, p<0.01.