Effects of pipeline optimization on group-level activation, <i>strong</i> contrast.

<p>Activation structure is shown for <i>strong</i> (Task vs. Control) contrast, under fixed (<b>FIX</b>) and individually-optimized (<b>IND</b>) preprocessing. (A) mean Z-scored activation maps for <b>FIX</b> and <b>IND</b> (top), and mean Z-score change (bottom), with significance given by bootstrap estimation (1000 iterations), thresholded at False-Discovery Rate (FDR) 0.05. (B) between-subject SPM correlations, for both <b>FIX</b> and <b>IND</b> pipeline sets. (C) between-subject Jaccard activation overlap, for voxels significant at FDR = 0.05. For (B–C), each point represents mean correlation/overlap of one subject with all others; blue lines show an increase in correlation/overlap with <b>IND</b>, and red lines show a decrease.