SM934 treatment induced the accumulation of Treg cells.
- Li-Fei Hou (180547)
- Shi-Jun He (180554)
- Xin Li (51274)
- Chun-Ping Wan (180562)
- Yang Yang (45629)
- Xiao-Hui Zhang (180568)
- Pei-Lan He (180572)
- Yu Zhou (89766)
- Feng-Hua Zhu (180578)
- Yi-Fu Yang (180584)
- Ying Li (38224)
- Wei Tang (53470)
- Jian-Ping Zuo (180592)
Publication date
February 2012
DOIAbstract
<p>At the termination of 3 months treatment, female NZB/W F<sub>1</sub> mice in vehicle and SM934 (10 mg/kg) treated groups were randomly and averagely divided into 3 sub-groups. Spleens of each sub-group were pooled together. (A) Surface CD4 and intracellular FoxP3 expressions in splenocytes. (B) Statistical results of percentage of CD4<sup>+</sup>FoxP3<sup>+</sup> population in splenocytes. (C) Real-time PCR analysis of FoxP3 mRNA expression in purified CD4<sup>+</sup> T cells. Shown are mean ± SD, n = 3 in each treated group. * = <i>P</i><0.05 versus vehicle.</p
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