Resolving conflicts.

<p>Effect of phosphoinositide feedback () versus absent feedback () and cell shape dynamics on the response of cells to competing, conflicting, or noisy stimuli. (a) “V” shaped gradient with static cell shape. (See <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002402#pcbi.1002402.s006" target="_blank">Video S6</a>). (b) “V” shaped gradient with dynamic shape changes. (See <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002402#pcbi.1002402.s007" target="_blank">Video S7</a>). (c) Noise-induced fronts within motile cells. (See <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002402#pcbi.1002402.s008" target="_blank">Video S8</a>). PIs allow the cell to rapidly resolve the competition between contradictory signals.