<p>(A) The mean and standard deviation of biomarker values are shown for three selected clusters generated with 4152 males 20 years of age or older from the NHANES training set, using the Z-score normalized/CLICK pre-processing/clustering combination. For each cluster, the total number of individuals (top, right) and selected health/lifestyle traits that are significantly enriched in that cluster (top, left) are provided. For each enriched term, the enrichment factor (i.e. the frequency of the term in a cluster divided by its frequency in the entire dataset) is also provided. (B) Comparison of the original values of selected biomarkers in clusters 1, 3 and 14. The values for Hb are enlarged in the top middle section of the figure.</p
Human ageing is a complex trait that involves the synergistic action of numerous biological processe...
Summary of cluster characteristics [median and interquartile range (IQR)] with respect to the age, h...
<p>Four examples of clusters are presented; for each, a phylogram and graphical representation of th...
<p>The NHANES code and description of validated terms found in clusters generated by pre-processing ...
<p>The number of validated terms found to be enriched in clusters generated with the different pre-p...
<div><h3>Motivation</h3><p>It has been proposed that clustering clinical markers, such as blood test...
<p>A test-validation approach was used to test the impact of methodological choices on the clusterin...
MOTIVATION: It has been proposed that clustering clinical markers, such as blood test results, can b...
¶<p>Data derived from national HTC registers of the 12 health centers in the study area.</p>§<p><i>p...
<p>(A) Characteristics of the cluster based on age. Green circle indicates 15–24 years old. Blue cir...
<p>(a) Mask generated from statistical analysis of <i>set level</i> contrast across young and older ...
<p>The demonstrate the of the variable when regressed on the remaining variables in the cluster to...
<p>P-values were calculated using chi-square of Fisher's exact tests, as appropriate (for the compar...
<p>*Remains significant after Bonferroni correction (8 independent tests)</p><p><sup>#</sup>P < 0.05...
<p>SES = socio-economic status</p><p>** p < .01</p><p><sup>a</sup> significantly different to M1 (p<...
Human ageing is a complex trait that involves the synergistic action of numerous biological processe...
Summary of cluster characteristics [median and interquartile range (IQR)] with respect to the age, h...
<p>Four examples of clusters are presented; for each, a phylogram and graphical representation of th...
<p>The NHANES code and description of validated terms found in clusters generated by pre-processing ...
<p>The number of validated terms found to be enriched in clusters generated with the different pre-p...
<div><h3>Motivation</h3><p>It has been proposed that clustering clinical markers, such as blood test...
<p>A test-validation approach was used to test the impact of methodological choices on the clusterin...
MOTIVATION: It has been proposed that clustering clinical markers, such as blood test results, can b...
¶<p>Data derived from national HTC registers of the 12 health centers in the study area.</p>§<p><i>p...
<p>(A) Characteristics of the cluster based on age. Green circle indicates 15–24 years old. Blue cir...
<p>(a) Mask generated from statistical analysis of <i>set level</i> contrast across young and older ...
<p>The demonstrate the of the variable when regressed on the remaining variables in the cluster to...
<p>P-values were calculated using chi-square of Fisher's exact tests, as appropriate (for the compar...
<p>*Remains significant after Bonferroni correction (8 independent tests)</p><p><sup>#</sup>P < 0.05...
<p>SES = socio-economic status</p><p>** p < .01</p><p><sup>a</sup> significantly different to M1 (p<...
Human ageing is a complex trait that involves the synergistic action of numerous biological processe...
Summary of cluster characteristics [median and interquartile range (IQR)] with respect to the age, h...
<p>Four examples of clusters are presented; for each, a phylogram and graphical representation of th...