<p>(<b>A</b>) Representative current traces of oocytes expressing WT or mutant BmOr-1 or BmOrco. Bombykol (1 µM) and MTSET (2.5 mM) were applied at the time indicated by arrowheads and blue squares, respectively. (<b>B</b>) Summary of effects of MTSET on the bombykol response of WT (black bar) and mutant BmOr-1 (gray bars). The mutant with a significant effect on ion permeability is colored in red (unpaired Student's t-test, mutant vs. WT **p<0.01). Data are shown as mean ± S.E.M., n = 5 <b>(see also <u><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0032372#pone.0032372.s004" target="_blank">Figure S4</a></u>)</b>.</p
<p>(<i>A</i>) Traces and (<i>B</i>) quantification of current responses obtained from the BmorOR1•Bm...
<p>The viability of the osmotically fragile strain MJF455 expressing MscL cysteine substituted mutan...
<p>GABA (EC<sub>10</sub>) was applied repetitively until a stable current response was observed foll...
<p>(<b>A</b>) Representative current-voltage (I–V) curves of oocytes expressing WT or mutant Or or B...
<p><b>A</b>. Effect of MTSET on wildtype or mutant ASIC1a expressed in <i>Xenopus</i> oocytes. MTSET...
<p>(<b>A</b>) Schematic of the location of amino acids in BmOr-1 and BmOrco that were mutated in thi...
<p>HeLa cells expressing single cysteine mutants or Cysteine-less EAAT1, were preincubated in NaCl-c...
<p>A–B: Sample traces from oocytes expressing either wild type rP2X2 (WT) or K69C as they were expos...
<p>A: Effect of suramin on an oocyte expressing wild type rP2X2 when applied without exogenous ATP. ...
<p>HeLa cells expressing the single cysteine mutants L296C (<b><i>A</i></b>), I297C (<b><i>B</i></b>...
<p><b>A–C</b>. Currents observed in oocytes expressing (<b>A</b>) WT-CALHM1, (<b>B</b>) G330D-CALHM1...
(A) rv0500A disruption enhances Mtb response to acidic pH and high [Cl-]. WT, rv0500A::Tn, or rv0500...
<p>(A) Summary of the average responses of BmOr-1-BmOrco-injected oocytes (left) and none-injected o...
<p>(A) Representative trace of WT Kv7.1 coexpressed with WT KCNE1. (B) Effects of external Cu-Phen o...
<p>In these experiments K69C expressing oocytes were first exposed to the test compound (50 µM, 5 mi...
<p>(<i>A</i>) Traces and (<i>B</i>) quantification of current responses obtained from the BmorOR1•Bm...
<p>The viability of the osmotically fragile strain MJF455 expressing MscL cysteine substituted mutan...
<p>GABA (EC<sub>10</sub>) was applied repetitively until a stable current response was observed foll...
<p>(<b>A</b>) Representative current-voltage (I–V) curves of oocytes expressing WT or mutant Or or B...
<p><b>A</b>. Effect of MTSET on wildtype or mutant ASIC1a expressed in <i>Xenopus</i> oocytes. MTSET...
<p>(<b>A</b>) Schematic of the location of amino acids in BmOr-1 and BmOrco that were mutated in thi...
<p>HeLa cells expressing single cysteine mutants or Cysteine-less EAAT1, were preincubated in NaCl-c...
<p>A–B: Sample traces from oocytes expressing either wild type rP2X2 (WT) or K69C as they were expos...
<p>A: Effect of suramin on an oocyte expressing wild type rP2X2 when applied without exogenous ATP. ...
<p>HeLa cells expressing the single cysteine mutants L296C (<b><i>A</i></b>), I297C (<b><i>B</i></b>...
<p><b>A–C</b>. Currents observed in oocytes expressing (<b>A</b>) WT-CALHM1, (<b>B</b>) G330D-CALHM1...
(A) rv0500A disruption enhances Mtb response to acidic pH and high [Cl-]. WT, rv0500A::Tn, or rv0500...
<p>(A) Summary of the average responses of BmOr-1-BmOrco-injected oocytes (left) and none-injected o...
<p>(A) Representative trace of WT Kv7.1 coexpressed with WT KCNE1. (B) Effects of external Cu-Phen o...
<p>In these experiments K69C expressing oocytes were first exposed to the test compound (50 µM, 5 mi...
<p>(<i>A</i>) Traces and (<i>B</i>) quantification of current responses obtained from the BmorOR1•Bm...
<p>The viability of the osmotically fragile strain MJF455 expressing MscL cysteine substituted mutan...
<p>GABA (EC<sub>10</sub>) was applied repetitively until a stable current response was observed foll...