Analysis of pronephric marker gene expression in larvae overexpressing P328L329del HNF1β mutation.

<p>Whole mount <i>in situ</i> hybridization of non-transgenic controls (A–F) and mutant animals (A′–F′) heat-shocked at early gastrula (stage 11) were performed for the indicated markers. Abbreviations: OT: otic vesicle: PT, proximal tubules; PD: pronephric duct; G: Quantitation of the marker gene expression domains in mutant and control animals. * = p<0.01 (Student's t-test). N refers to the number of measurements performed.