Celecoxib caused cell cycle arrest at G1 phase in NTUB1 and T24 UC cells.

<p>(A) NTUB1 and T24 cells were treated with mock (untreated) or celecoxib (100 µM) for 12 and 24 h, and cell cycle analysis was measured as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033615#s2" target="_blank">Materials and methods</a>. Data are presented as means ± SD of three independents experiments. * p<0.05 as compared with control. (B) The expressions of p21 and p27 at 12 and 24 h after celecoxib treatment were analyzed by Western blotting. Results shown are representative of at least three independent experiments.