Cluster analysis for the reported transcript sets.

<p>K-means cluster analysis based upon the transcript sets reported by (A) Lequerré (20 genes) (B) Stuhlmuller (11 genes) (C) Stuhlmuller (82 genes) (D) Lequerré (8 genes) (E) Sekiguchi (18 genes) (F) Julia (8 genes) (G) Stuhlmuller (3 genes) and (H) Tanino (8 genes). The previously published transcript sets were linked to the expression values of 42 RA patients treated with anti-TNF in our study. The two clusters were identified as the non-responder (1) and responder (2) clusters. Profiles are ranked according the results obtained after clustering, in which profile A showed the best results. • = responder; ○ = non-responder.