mRNA expression of pro-inflammatory genes following acute administration of 10 mg/kg MPH in the striatum.

<p>Fold change values in mRNA expression presented are normalized against saline controls, in the striatum. The genes probed for include (A) <i>il-6</i>, (B) <i>tnf-á</i>, (C) <i>cox2</i> and (D) <i>il-1b</i>. *p≤0.02 compared to saline-controls (ctrl); **p≤0.02 compared to 10 mg/kg MPH-chronic dose, (n = 3). One-way ANOVA statistical test was performed to draw comparisons between the different groups followed by Bonferroni post-hoc tests.