Apoptotic and cell proliferation effects of chronic exposure to Cd on mouse livers.

<p>Liver samples were collected as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033853#pone-0033853-g003" target="_blank">Figure 3</a> for TUNEL staining with semi-quantitative evaluation (A). Apoptotic effect was further confirmed with cleaved-CASP3 (c-CASP3), detected by Western blot (B). Ki-67 measurement with immunohistochemical staining (C) and Western blot (D). The images for each group are the representative ones. Bar = 50 µm. Data was presented as mean ± SD (n = 10). * <i>p</i><0.05 vs control; # <i>p</i><0.05 vs Cd group.