Behavior of the ratio of the mean and standard deviation of the time between reactions in the presence of confining domains to that in the absence of confining domains, denoted by

<p><b> and </b><b>, respectively (see text).</b> Data obtained by Monte Carlo simulations. <b>a.</b> the dependence of and on confinement strength characterized by . takes on values between and . Other parameter values are: , , , , . <b>b. </b> and as a function of reaction probability , with other parameters fixed at: , , , , . <b>c.</b> density dependence of and . In this case , , , , and the density varies between 0.05 and 2 molecules per compartment. Error bars in all plots are smaller than the data points.