META060 reduces high-fat diet-induced body weight gain and fat mass development.

<p>(<b>A</b>) Body weight gain (g) evolution, <i>inset</i> correspond to total body weight gain, (<b>B</b>) cumulative food intake (g), (<b>C</b>) subcutaneous, (<b>D</b>) visceral, (<b>E</b>) epididymal adipose tissues weight, and (<b>F</b>) adiposity index (corresponding to the sum of the three adipose depots) expressed as the percentage of total body weight of mice fed a control diet (CT), high-fat diet (HFD) or high-fat diet supplemented with 0.1% META060 (HFD-META060). n = 10 mice/group. Data are expressed as mean ± SEM. Different superscript letters were significantly different (P<0.05) according to one-way ANOVA. Interaction Treatment×Time P<0.0001; Treatment P<0.0001; Time P<0.0001. *P<0.05 HFD versus CT, $P<0.05 HFD-Meta versus HFD, #P<0.05 HFD-Meta versus CT according to Two-way ANOVA.