Canonical correlation analysis of RNA and protein temporal expression profiles.

<p>A) Ranked canonical correlations between RNA expression and protein expression, compared with random permutations. Each gray line shows the computed canonical correlations for a single random permutation. The first observed canonical correlation exceeds all corresponding permuted values, and the second canonical correlation exceeds 99% of permuted values; both are considered statistically significant. B) Scatter plot of first canonical variable between RNA and protein expression for 199 gene/protein pairs with a correlation coefficient of 0.44.