The effect of the Gd-C₅F₁₂-PLN-100 on HIFU tumor ablation in the subcutaneous tumor model.

<p>The tumor ablation by HIFU was monitored by gadolinium -enhanced T1-weighted imaging before and after HIFU treatment. The contrast-enhanced images were subtracted from the image before enhancement. The arrow indicates the HIFU orientation (upper panel). The HIFU ablation was also examined by H&E and NADH staining of frozen specimens to confirm the ablated area (lower panel).