<p>a. Representative images of the lung tissue sections. Insert - higher magnifigation (2.5× zoom) of a field illustrating the presence of SWCNT (green punctuate spots pointed by white arrows). b. Quantitation of SWCNT aggregates (SWCNT volume/total lung volume) using their specific absorbance (750–850 nm), * p<0.05, <i>vs</i> w/t 1 day post exposure, # p<0.05, <i>vs</i> w/t 28 days post exposure. c. Assessment of SWCNT aggregates - number per microscopic field - using an automated IN Cell Analyser 1000 microscope, * p<0.05, <i>vs</i> w/t 1 day post exposure, # p<0.05, <i>vs</i> w/t 28 days post exposure.</p
<p>Main bronchi of mouse living lung sections were analyzed by two-photon time-lapse microscopy. (A)...
<p>(A) Representative lung parenchyma from an air-control <i>p66</i><sup><i>Shc−/−</i></sup> mouse s...
Background Inhalation exposure studies of mice were conducted to determine if multi-walled carbon na...
<p>ransmission electron <b>microscopy.</b> a. Typical TEM images of SWCNT after solubilization of th...
<p>a. Accumulation of collagen in the lung of w/t or MPO k/o mice. Mean ± SEM (n = 6 mice/group). *p...
<p>(A) Whole mouse lung inflated with 10% low-melt agarose, trachea folded forward, and general regi...
<p>A. Representative images of RV section showing H& E staining (upper panel). The lower panel is sh...
<p>(<b>A</b>) Lung tissue sections of mice 7 days after intravenous injection with carbon nanomateri...
BackgroundInhalation exposure studies of mice were conducted to determine if multi-walled carbon nan...
Lung tissues at 12 months after T-CNT exposure were collected and tissue sections were stained with ...
(A) Representative images of the lung sections stained with Masson’s trichrome were taken at 20x mag...
<p>(A) The crucial steps of the automated analysis protocol are illustrated in a normal and a fibrot...
Purpose: Multi-walled carbon nanotubes (MWCNTs) are nano-scale fibrous particles that are increasing...
<p>a–c. Levels of pro-inflammatory cytokines (a - TNF-α; b - IL-6; c – MCP-1) in BAL fluid of w/t an...
<p>The collected lung tissue samples from each group of mice at 4 d.p.i. were subjected to routine h...
<p>Main bronchi of mouse living lung sections were analyzed by two-photon time-lapse microscopy. (A)...
<p>(A) Representative lung parenchyma from an air-control <i>p66</i><sup><i>Shc−/−</i></sup> mouse s...
Background Inhalation exposure studies of mice were conducted to determine if multi-walled carbon na...
<p>ransmission electron <b>microscopy.</b> a. Typical TEM images of SWCNT after solubilization of th...
<p>a. Accumulation of collagen in the lung of w/t or MPO k/o mice. Mean ± SEM (n = 6 mice/group). *p...
<p>(A) Whole mouse lung inflated with 10% low-melt agarose, trachea folded forward, and general regi...
<p>A. Representative images of RV section showing H& E staining (upper panel). The lower panel is sh...
<p>(<b>A</b>) Lung tissue sections of mice 7 days after intravenous injection with carbon nanomateri...
BackgroundInhalation exposure studies of mice were conducted to determine if multi-walled carbon nan...
Lung tissues at 12 months after T-CNT exposure were collected and tissue sections were stained with ...
(A) Representative images of the lung sections stained with Masson’s trichrome were taken at 20x mag...
<p>(A) The crucial steps of the automated analysis protocol are illustrated in a normal and a fibrot...
Purpose: Multi-walled carbon nanotubes (MWCNTs) are nano-scale fibrous particles that are increasing...
<p>a–c. Levels of pro-inflammatory cytokines (a - TNF-α; b - IL-6; c – MCP-1) in BAL fluid of w/t an...
<p>The collected lung tissue samples from each group of mice at 4 d.p.i. were subjected to routine h...
<p>Main bronchi of mouse living lung sections were analyzed by two-photon time-lapse microscopy. (A)...
<p>(A) Representative lung parenchyma from an air-control <i>p66</i><sup><i>Shc−/−</i></sup> mouse s...
Background Inhalation exposure studies of mice were conducted to determine if multi-walled carbon na...