IFN-γ responsiveness of lymphoma cells is not required for antigen-dependent lymphoma rejection.
- Armin Gerbitz (174530)
- Madhusudhanan Sukumar (174539)
- Florian Helm (174546)
- Andrea Wilke (174556)
- Christian Friese (174562)
- Cornelia Fahrenwaldt (174572)
- Frank M. Lehmann (174583)
- Christoph Loddenkemper (23477)
- Thomas Kammertoens (174596)
- Josef Mautner (10677)
- Clemens A. Schmitt (174610)
- Thomas Blankenstein (50668)
- Georg W. Bornkamm (10665)
Publication date
March 2012
DOIAbstract
<p>IFN-γ-receptor-deficient λ-huMYC lymphoma cells, either retrovirally transduced (50OVA) (solid line) or untransduced (50PC) (dashed line), were injected s.c. into wild-type mice. STAT1-deficient mice inoculated with retrovirally transduced 50OVA cells served as positive control (dotted line). Mice were monitored for survival (left panel) and cumulative tumor growth (right panel). The data are combined from 2 independent experiments.</p
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