Effects of tanshinones on survivin and Aurora A protein levels in breast cancer cells (48 h).

<p>A: Representative western blot images showing survivin and Aurora A protein levels in breast cancer cell lines (MCF-7, MDA-MB231, SKBR3, MDA-MB453) following tanshinone treatments with β-actin as the loading control; B and C: Quantitation of Aurora A (B) and survivin (C) protein levels by densitometry after normalization to β-actin. Values were mean±SEM of three independent experiments in duplicates. The images for quantitation were from at least two independent experiments. Within the panel, the value with a letter was significantly different from that of the corresponding control, a, p<0.05; b, p<0.01; c, p<0.001.