Overview of the experimental design.

<p>A cross between laboratory (BY) and wild (RM) strains of <i>S. cerevisiae </i><a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001301#pbio.1001301-Brem1" target="_blank">[11]</a> was gene expression profiled. Metabolites were profiled under the same conditions. These data were then integrated with genotype data along with information from public databases to derive a BN. The derived network was used to analyze how cells are regulated.