<p>Feces were collected from WT and Oatp1a1-null mice for 24 hr and dried under vacuum. The concentrations of primary BAs (a, b, and c) and secondary BAs (d, e, and f) in the feces of male WT and Oatp1a1-null mice (n = 5/group) were analyzed using ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) and normalized by fecal dry weight. All data are expressed as mean ± S.E. of five mice in each group. *, statistically significant difference between WT and Oatp1a1-null mice (<i>p</i><0.05).</p
<p>CA and DCA as well as their taurine-conjugates have –OH group at 12α-C position, and therefore ar...
<p>(A) Concentrations of individual unconjugated BAs in serum during aging and (B) proportions of th...
<p>HPLC analysis was performed using day 21 samples, which showed the greatest difference among each...
<p>BA concentrations in the intestinal contents of male WT and Oatp1a1-null mice (n = 5/group) were ...
<p>BA concentrations in livers and bile of male WT and Oatp1a1-null mice (n = 5/group) were analyzed...
<p>Clostridia (a), Bacteroides (b), Lactobacilli (c), and other bacteria (d) in the small and large ...
<p>Sirt1-LKO, WT, and Sirt1-TG mice were given ad libitum (AL) or 40% CR feeding (n = 5) for one mon...
<div><p>Organic anion transporting polypeptide 1a1 (Oatp1a1) is predominantly expressed in liver and...
The pattern of metabolites produced by the gut microbiome comprises a phenotype indicative of the me...
The pattern of metabolites produced by the gut microbiome comprises a phenotype indicative of the me...
The pattern of metabolites produced by the gut microbiome comprises a phenotype indicative of the me...
<p>Fecal metabolites that were differentially abundant in RM as compared to CM only in WT mice.</p
The pattern of metabolites produced by the gut microbiome comprises a phenotype indicative of the me...
<p>(A) Concentrations of individual unconjugated BAs in liver during aging and (B) proportions of th...
<p>Validated fecal metabolites that were differentially abundant in RM as compared to CM in the Atm-...
<p>CA and DCA as well as their taurine-conjugates have –OH group at 12α-C position, and therefore ar...
<p>(A) Concentrations of individual unconjugated BAs in serum during aging and (B) proportions of th...
<p>HPLC analysis was performed using day 21 samples, which showed the greatest difference among each...
<p>BA concentrations in the intestinal contents of male WT and Oatp1a1-null mice (n = 5/group) were ...
<p>BA concentrations in livers and bile of male WT and Oatp1a1-null mice (n = 5/group) were analyzed...
<p>Clostridia (a), Bacteroides (b), Lactobacilli (c), and other bacteria (d) in the small and large ...
<p>Sirt1-LKO, WT, and Sirt1-TG mice were given ad libitum (AL) or 40% CR feeding (n = 5) for one mon...
<div><p>Organic anion transporting polypeptide 1a1 (Oatp1a1) is predominantly expressed in liver and...
The pattern of metabolites produced by the gut microbiome comprises a phenotype indicative of the me...
The pattern of metabolites produced by the gut microbiome comprises a phenotype indicative of the me...
The pattern of metabolites produced by the gut microbiome comprises a phenotype indicative of the me...
<p>Fecal metabolites that were differentially abundant in RM as compared to CM only in WT mice.</p
The pattern of metabolites produced by the gut microbiome comprises a phenotype indicative of the me...
<p>(A) Concentrations of individual unconjugated BAs in liver during aging and (B) proportions of th...
<p>Validated fecal metabolites that were differentially abundant in RM as compared to CM in the Atm-...
<p>CA and DCA as well as their taurine-conjugates have –OH group at 12α-C position, and therefore ar...
<p>(A) Concentrations of individual unconjugated BAs in serum during aging and (B) proportions of th...
<p>HPLC analysis was performed using day 21 samples, which showed the greatest difference among each...