The ratio of structural disorder within and outside Pfam domains.

<p>The average ratio of disordered residues (with a score ≥0.5) in proteins of the eukaryotic proteomes, within regions outside Pfam domains is shown as a function the same value within Pfam domains. Large phylogenetic groups are color coded, as defined on a small plate. The linear function showing a parallel increase of disorder within and outside Pfam domains in most species is marked by a dashed line. Certain groups of species show significant deviation from this linear dependence, as explained and discussed in the text.