GH effects on chondrocyte autophagy.
- Óscar Álvarez-García (172776)
- Enrique García-López (172780)
- Vanessa Loredo (172784)
- Helena Gil-Peña (172788)
- Natalia Mejía-Gaviria (172792)
- Julián Rodríguez-Suárez (172799)
- Flor Á. Ordóñez (172805)
- Fernando Santos (106077)
Publication date
April 2012
DOIAbstract
<p>(A) Immunofluorescent detection of LC3, a marker of autophagy, in the growth plates of rats treated with rapamycin (RAPA) or rapamycin and GH (RGH). Fluorescent signal was observed in prehypertrophic chondrocytes often displaying a punctuate distribution (white arrows in B). (C) Western blot of LC3-I (18 kDa) and LC3-II (16 kDa) in the growth cartilage of rats treated with rapamycin (RAPA) or rapamycin and GH (RGH). GAPDH was used as loading control. Image is representative of three blots giving similar results.</p
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