Summary of significant genetic regulation in the hippocampus.

<p>Probe sets represent columns and ascending genomic location for each chromosome represent rows. Only chromosomes with a significant QTL (LRS>15) are shown. Several GABA(A)R subunits are regulated by both <i>cis</i> and <i>trans</i> eQTL (<i>Gabra1</i>, <i>Gabra2</i>, <i>Gabrb2</i>, and <i>Gabrb3</i>) whereas some are modified exclusively in <i>trans</i> (<i>Gabra5</i>, <i>Gabrg1</i>). Hue intensity provides an indication of the strength of the association between gene expression and genomic location. Red and blue alleles indicate that the <i>D</i> or <i>B</i> allele increases trait values, respectively. Arrowheads show the location of each cognate gene. PC1 = first principal component, Chr = Chromosome, Mb = Megabase, Prox = proximal, mid = middle, dist = distal.