<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034565#pone-0034565-g002" target="_blank">Figure 2</a> Illustrates of the extent of haplotype homogeneity in the haplotypes observed in HbC, HbS and HbA chromosomes in the study. The chromosomes are represented on the Y axis and 51 SNPs analysed in a 2 Mb region across the HbS locus represented on the X axis. For each of the 51 markers, major and minor alleles are coded orange and blue respectively. The 51 markers are arranged according to their position in the β globin gene region.</p
We present a simple two-stage procedure to define haplotype blocks and construct a statistic to test...
Objective: Analyze the information contained in homozygous haplotypes detected with high density gen...
<p>This figure was obtained using statistical parsimony analysis within TCS, v.1.21 [<a href="http:/...
<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034565#pone-0034565-g003" ...
<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034565#pone-0034565-t002" ...
Previous investigations have reported linkage disequilibrium occurring between nearby polymorphisms,...
<p><b>Copyright information:</b></p><p>Taken from "Mutation and evolutionary analyses identify candi...
Five major β-globin locus haplotypes have been established in individuals with sickle cell disease (...
<p>The alignment covers the centromeric side of the DR–DQ 158-kb DNA segment (left half, low variati...
<p>The estimated recombination rate (in centimorgans per megabase) is shown as a dark blue line, wit...
<p>Panels on the left represent the decay of EHH, or the probability of homozygosity at a certain ba...
PubMedID: 1577473We have determined the ßs haplotypes in 709 patients with sickle cell anemia, 30 wi...
Analysis of the 5? and 3? haplotypes (Hps) of the ?-globin gene cluster was performed in 110 ?A chro...
Genetic variation at the human a-globin gene complex has only been characterised to date ...
<p>Lines represent two reconstructed haplotypes for each individual. The data are displayed as custo...
We present a simple two-stage procedure to define haplotype blocks and construct a statistic to test...
Objective: Analyze the information contained in homozygous haplotypes detected with high density gen...
<p>This figure was obtained using statistical parsimony analysis within TCS, v.1.21 [<a href="http:/...
<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034565#pone-0034565-g003" ...
<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034565#pone-0034565-t002" ...
Previous investigations have reported linkage disequilibrium occurring between nearby polymorphisms,...
<p><b>Copyright information:</b></p><p>Taken from "Mutation and evolutionary analyses identify candi...
Five major β-globin locus haplotypes have been established in individuals with sickle cell disease (...
<p>The alignment covers the centromeric side of the DR–DQ 158-kb DNA segment (left half, low variati...
<p>The estimated recombination rate (in centimorgans per megabase) is shown as a dark blue line, wit...
<p>Panels on the left represent the decay of EHH, or the probability of homozygosity at a certain ba...
PubMedID: 1577473We have determined the ßs haplotypes in 709 patients with sickle cell anemia, 30 wi...
Analysis of the 5? and 3? haplotypes (Hps) of the ?-globin gene cluster was performed in 110 ?A chro...
Genetic variation at the human a-globin gene complex has only been characterised to date ...
<p>Lines represent two reconstructed haplotypes for each individual. The data are displayed as custo...
We present a simple two-stage procedure to define haplotype blocks and construct a statistic to test...
Objective: Analyze the information contained in homozygous haplotypes detected with high density gen...
<p>This figure was obtained using statistical parsimony analysis within TCS, v.1.21 [<a href="http:/...