Decreased bone strength in TTD mice.
- Claudia Nicolaije (172380)
- Karin E. M. Diderich (172384)
- S. M. Botter (172390)
- Matthias Priemel (172395)
- Jan H. Waarsing (172400)
- Judd S. Day (172405)
- Renata M. C. Brandt (172411)
- Arndt F. Schilling (172417)
- Harrie Weinans (6823)
- Bram C. Van der Eerden (172423)
- Gijsbertus T. J. van der Horst (70178)
- Jan H. J. Hoeijmakers (172432)
- Johannes P. T. M. van Leeuwen (61542)
Publication date
April 2012
DOIAbstract
<p>Bone strength, mineralization, perimeter, MOI and bone formation rates in long bones of aging wild type (solid bars or symbols) and TTD males (open bars or symbols). (A) Energy to failure (B) Ultimate load (C) Bone stiffness, (D) bone mineralization, (C) MOI and (D) perimeter (Pm.). Statistics: a= student t-test; p<0.05 wild type vs. TTD, b−d = 2 way ANOVA; p<0.05. b= significant difference between wild type and TTD with aging, c= signifcant difference with aging within a genotype, d= a significant interaction between age and genotype. Error bars represent SEM.</p
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