GSEA of MYC target genes in tumors characterized for MYC protein expression;

<p>(<b>A</b>). Gene Set Enrichment Analysis (GSEA) of all primary DLBCL cases reveals coordinate upregulation of MYC and MYC target genes (black vertical lines) in tumors with >50% MYC positive tumor nuclei (including <i>MYC</i> translocation-positive and –negative cases) (See Supplementary <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033813#pone.0033813.s006" target="_blank">Methods S1</a> for additional details). <b>Gene Set Enrichment Analysis (GSEA) of MYC-target genes in </b><b><i>MYC</i></b><b> translocation–negative Primary DLBCL tumors;</b> (<b>B</b>) <i>MYC</i> translocation-negative primary DLBCL cases with >50% MYC positive tumor nuclei have coordinate upregulation of MYC and MYC target genes (black vertical lines).