Core body temperature regulation is altered in <i>Mecp2^−/+</i> mice.

<p>Panel A: Scatter plot showing the range of core body temperature in <i>Mecp2^−/+</i> and wild-type mice. Each point represents the absolute range (min to max during the 24-hour day) of core body temperature for an individual mouse. On Panel A, # denotes p<0.05 as determined using an F-test for the equality of two variances. Panel B and C: Histograms showing the mean ± SEM of the active body temperature of <i>Mecp2^−/+</i> and wild-type mice (B), and their average inactive body temperature (C) throughout the day, or specifically during the light or dark phases. Panel D: Scatter plot showing the Pearson's product-moment correlation coefficients for mobility and temperature in <i>Mecp2^−/+</i> and wild-type mice. Each point represents the daily correlative strength between mobility and temperature for a single subject. The bar on the scatter plot indicates the mean for each set. Asterisks denote statistical significance (p<0.05) between the indicated groups (student's unpaired t-test). n = 11 <i>Mecp2^−/+</i> mice and n = 7 wild-type mice.