SAA decreases the expression of adipocyte markers.

<p>hMADS adipocytes were cultured in the presence or absence of human recombinant SAA (1, 3, 10 and 30 µg/mL) for 24 h. Upon treatment, total RNA was extracted and expression levels of various genes were analyzed by RTqPCR. Panel A: three important transcription factor (PPARγ2, C/EBPα and SREBP-1c). Panel B: lipogenic genes and adiponectin. Panel C: inflammation related proteins. The mRNA levels, normalized to LRP10 RNA expression, were determined relative to untreated control cells. Data are expressed as mean ± SD from n = 3–5 independent experiments. Statistical significance: * <i>p</i><0.05; ** <i>p</i><0.01; *** <i>p</i><0.001 vs. control.