Visualization of the two synthetic SNP-genotype combinations and their high-order association with the two classes.

<p>The two subfigures in the left column are the visualization of the genotypes of 4 SNPs separated by vertical green lines, over the 70 cases and 70 controls separated by a horizontal yellow line. The black color indicates present and the white indicates absent, in the binary format described in the method section. The statistic, odds ratios and the fisher exact test p value of the two combinations are ( and respectively. Each subfigure in the right column contains 4 pairs of bars. For each pair, the unfilled bar and the filled bar indicate the minimal and the maximal statistics for the size-<i>i</i> () subsets of the combination. The right most pair, both bars are equal since they both denote the statistic of the SNP combination itself. Another four examples of high-order discriminative SNP combinations of size-36 are shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033531#pone.0033531.s002" target="_blank">Figure S2</a> with similar description as this figure.