<p>Mice (n = 3/group) received a single IV injection of MTM-SK (A) or MTM-SDK (B) and plasma levels were determined by LC-MS. Doses of MTM-SK and MTM-SDK were 18 mg/kg and 2 mg/kg, respectively.</p
<p>Pharmacokinetic parameter estimates for mice, rats, and dogs obtained by simultaneously fitting o...
<p>(A) Mice were injected <i>intravenously</i> with a bolus injection of DMS5540 at 0.1 (red), 1.0 (...
<p>PK profiles of HC-070 after intravenous (A) and oral (B) administration in C57BL/6 mice. Plasma c...
<p>50 µg of purified antibody was intraperitoneally injected into Swiss mice (n = 3 or 4). Mice were...
<p>Ivermectin (IVM) or moxidectin (MOX) was administered subcutaneously in Mdr1ab(−/−) mice (6 per d...
<p>Mice with subcutaneous tumors were treated with the indicated doses of MTM-SDK, MTM-SK or sterile...
<p>Plasma, skin, and intestine samples were collected from the mice orally administered 30 mg/kg Com...
<p>Pharmacokinetic Parameters of Compounds <b>7c</b> and <b>7m</b> in Male ICR Mice.</p
These were the metabonomics data from KPC mice which were divided into 8 groups and administered wi...
<p>6–8 week old NSG mice (n = 6) were (<b>a</b>), administered MTX by i.p. injection at 25 mg/kg/day...
<p>IVM (filled squares) or MOX (empty squares) was administered to Mdr1ab(−/−) mice or to wild-type ...
<p>Plasma was collected over a period of 15 minutes—48 hours after M10 injection and measured by ind...
<p>Mice (n = 4/group) with subcutaneous tumors were treated with a single IV injection of MTM-SDK, M...
<p>Pharmacokinetic parameters for compound 4 and 5 based on oral administration in mice.</p
<p>Plasma concentration versus time profiles of KMS88009 following IV or PO administration to (A) mi...
<p>Pharmacokinetic parameter estimates for mice, rats, and dogs obtained by simultaneously fitting o...
<p>(A) Mice were injected <i>intravenously</i> with a bolus injection of DMS5540 at 0.1 (red), 1.0 (...
<p>PK profiles of HC-070 after intravenous (A) and oral (B) administration in C57BL/6 mice. Plasma c...
<p>50 µg of purified antibody was intraperitoneally injected into Swiss mice (n = 3 or 4). Mice were...
<p>Ivermectin (IVM) or moxidectin (MOX) was administered subcutaneously in Mdr1ab(−/−) mice (6 per d...
<p>Mice with subcutaneous tumors were treated with the indicated doses of MTM-SDK, MTM-SK or sterile...
<p>Plasma, skin, and intestine samples were collected from the mice orally administered 30 mg/kg Com...
<p>Pharmacokinetic Parameters of Compounds <b>7c</b> and <b>7m</b> in Male ICR Mice.</p
These were the metabonomics data from KPC mice which were divided into 8 groups and administered wi...
<p>6–8 week old NSG mice (n = 6) were (<b>a</b>), administered MTX by i.p. injection at 25 mg/kg/day...
<p>IVM (filled squares) or MOX (empty squares) was administered to Mdr1ab(−/−) mice or to wild-type ...
<p>Plasma was collected over a period of 15 minutes—48 hours after M10 injection and measured by ind...
<p>Mice (n = 4/group) with subcutaneous tumors were treated with a single IV injection of MTM-SDK, M...
<p>Pharmacokinetic parameters for compound 4 and 5 based on oral administration in mice.</p
<p>Plasma concentration versus time profiles of KMS88009 following IV or PO administration to (A) mi...
<p>Pharmacokinetic parameter estimates for mice, rats, and dogs obtained by simultaneously fitting o...
<p>(A) Mice were injected <i>intravenously</i> with a bolus injection of DMS5540 at 0.1 (red), 1.0 (...
<p>PK profiles of HC-070 after intravenous (A) and oral (B) administration in C57BL/6 mice. Plasma c...
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