Parameters used and number of significant patterns discovered for each of the three datasets, for evaluating the effects of gene-set constraints on enhancing statistical power after correcting multiple hypothesis tests.

<p>Parameters used and number of significant patterns discovered with respect to the FDR cutoff for each of the three approaches (A: without constraint, ; B: with constraints, and C: with constraints, ) on each of the four real datasets. The number outside the brackets are the number of significant patterns discovered, and the first number inside a bracket shows the number of unique SNPs covered by the patterns (note that there are overlaps between patterns); the second number inside the s bracket (for approaches B and C only) indicates the number of SNPs that are discovered by approaches B or C but not by approach A in the corresponding dataset, thus indicating the benefit of using gene-set constraints.